Structure of PDB 7m4v Chain E

Receptor sequence

>7m4vE (length=200) Species: 480119 (Acinetobacter baumannii AB0057)

MNLKTVSGSAVELSEVAFGREFNEALVHQVVTAYLAGGRQGTRAHKSRAD
VSGGGKKPFRQKGTGRARAGSIRSPIWVGGGKTFAARPQDWSQKVNRKMY
RGAMQCILAELVRQDRLVLVEEFAVAAPKTKELLAKLNDLNAARALIVTD
AVDENLYLAARNLPHVDVVDATAIDPVSLIAFDKVVMSVAAAKKIEVELG

3D structure

• PDB: 7m4v Cryo-EM Determination of Eravacycline-Bound Structures of the Ribosome and the Multidrug Efflux Pump AdeJ of Acinetobacter baumannii.
• Chain: E
• Resolution: 2.54 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	H28 Q29 Y34 L35 R39 Q40 T42 R43 H45 K46 R48 A49 V51 S52 G53 K57 Q61 K62 G63 G65 R66 A67 R68 G70 R73 I76 W77 V78 G79 K82 T83 F84 Q89 K94 N96 K98 M99 Y100 P128 K129 T130 L158 R161 N162 P164	H28 Q29 Y34 L35 R39 Q40 T42 R43 H45 K46 R48 A49 V51 S52 G53 K57 Q61 K62 G63 G65 R66 A67 R68 G70 R73 I76 W77 V78 G79 K82 T83 F84 Q89 K94 N96 K98 M99 Y100 P128 K129 T130 L158 R161 N162 P164

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7m4v, PDBe:7m4v, PDBj:7m4v
• PDBsum: 7m4v
• PubMed: 34044590
• UniProt: B7IA38|RL4_ACIB5 Large ribosomal subunit protein uL4 (Gene Name=rplD)