Structure of PDB 7lok Chain E

Receptor sequence
>7lokE (length=353) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
LWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQE
IHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLNTSAITQA
CPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHGIKPV
VSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNIRQA
HCNVSKATWNETLGKVVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCG
GEFFYCNTSGLFNSTWISDSITLPCRIKQIINMWQRIGQAMYAPPIQGVI
RCVSNITGLILTRDGGSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGV
APT
3D structure
PDB7lok Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
ChainE
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E V255 S256 G366 G367 D368 S375 F376 D474 V151 S152 G237 G238 D239 S246 F247 D328
BS02 MAN E V208 G379 V104 G250
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7lok, PDBe:7lok, PDBj:7lok
PDBsum7lok
PubMed33782388
UniProtQ2N0S6

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