Structure of PDB 7l6n Chain E

Receptor sequence
>7l6nE (length=548) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVRGEFEERLKAVL
DDIKNSAGQIITFIDELHTIVGNMIKPMLARGELRLVGATTLDEYRKHIE
KDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAA
TLSDRYITARFLPDKAIDLVDEAASRLRMEIDKEEVGPDDIADVVSAWTG
IPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPN
RPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHTVAR
LIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLD
EGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFINRL
DDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLAQRG
FDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADSL
3D structure
PDB7l6n Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainE
Resolution7.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E R252 G654 Y655 R89 G357 Y358
BS02 AGS E D178 P179 V180 I181 E207 P208 G209 V210 G211 K212 T213 I350 D20 P21 V22 I23 E49 P50 G51 V52 G53 K54 T55 I175
BS03 ADP E I573 T609 G610 V611 G612 T614 I764 I276 T312 G313 V314 G315 T317 I467
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l6n, PDBe:7l6n, PDBj:7l6n
PDBsum7l6n
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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