Structure of PDB 7kpe Chain E

Receptor sequence
>7kpeE (length=295) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence]
NIIIGAMTALITPFKNGKVDEQSYARLIKRQIENGIDAVVPVGTTGESAT
LTHEEHRTCIEIAVETCKGTKVKVLAGAGSNATHQAVGLAKFAKEHGADG
ILSVAPYYNKPTQQGLYEHYKAIAQSVDIPVLLYNVPGRTGCEISTDTII
KLFRDCENIYGVKEASGNIDKCVDLLAHEPRMMLISGEDAINYPILSNGG
KGVISVTSNLLPDMISALTHFALDENYKEAKKINDELYNINKILFCESNP
IPIKTAMYLAGLIESLEFRLPLCSPSKENFAKIEEVMKKYKIKGF
3D structure
PDB7kpe THE ALLOSTERIC SITE RESIDUE, E88 INTERACTS WITH THE INHIBITORS TO TRANSMIT THE ALLOSTERIC INHIBITION SIGNALS IN Cj.DHDPS BY FORMING A HYDROGEN BOND.
ChainE
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E G82 L105 S106 V107 G79 L102 S103 V104
BS02 3VN E S51 A52 N84 Y110 S48 A49 N81 Y107
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:7kpe, PDBe:7kpe, PDBj:7kpe
PDBsum7kpe
PubMed
UniProtQ9PPB4|DAPA_CAMJE 4-hydroxy-tetrahydrodipicolinate synthase (Gene Name=dapA)

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