Structure of PDB 7k9s Chain E

Receptor sequence
>7k9sE (length=210) Species: 5207 (Cryptococcus neoformans) [Search protein sequence]
STETFGFQAEISQLLDLIINTFYSNKEIFLRELISNSSDALDKIRYAALT
DPSQLDSEKDLYIRIIPNKEEGTLTIRDTGIGMTKADLVNNLGTIAKSGT
KAFMEALSSGADISMIGQFGVGFYSSYLVAEKVQVTTKHNDDEQYIWESA
AGGTFTITEDTEGPRLGRGTSMKLFIKEDLKEYLEEKRIREIVKKHSEFI
SYPIQLVVTK
3D structure
PDB7k9s Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity.
ChainE
Resolution3.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2GJ E N37 S38 A41 K44 D79 I82 G83 M84 F124 T171 M173 N36 S37 A40 K43 D78 I81 G82 M83 F123 T170 M172
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:7k9s, PDBe:7k9s, PDBj:7k9s
PDBsum7k9s
PubMed33444025
UniProtJ9VVA4

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