Structure of PDB 7jre Chain E

Receptor sequence
>7jreE (length=142) Species: 42789 (enterovirus D68) [Search protein sequence]
GPGFGGVFVGSFKIINYHLATIEERQSAIYVDWQSDVLVTPIAAHGRHQI
ARCKCNTGVYYCRHRDKSYPVCFEGPGIQWIEQNEYYPARYQTNVLLAAG
PAEAGDAGGLLVCPHGVIGLLTAGGGGIVAFTDIRNLLWLDT
3D structure
PDB7jre Crystal structure of EV-D68 2A protease C107A mutant
ChainE
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN E C53 C55 C113 H115 C53 C55 C113 H115
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016032 viral process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7jre, PDBe:7jre, PDBj:7jre
PDBsum7jre
PubMed
UniProtQ68T42|POLG_HED68 Genome polyprotein

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