Structure of PDB 7jn3 Chain E

Receptor sequence
>7jn3E (length=269) Species: 269446 (Rous sarcoma virus (strain Schmidt-Ruppin A)) [Search protein sequence]
PLREAKDLHTALHIGPRALSKACNISMQQAREVVQTCPHCNSAPALEAGV
NPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVA
VQHHWATAIAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNS
QGQAMVERANRLLKDKIRVLAEGDGFMKRIPTSKQGELLAKAMYALNHFE
RGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVK
NRDTDKVIWVPSRKVKPDI
3D structure
PDB7jn3 Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
ChainE
Resolution3.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E G49 V50 N51 P52 T143 I146 Q151 A154 R158 L162 E203 R244 Y246 G49 V50 N51 P52 T143 I146 Q151 A154 R158 L162 E203 R244 Y246
BS02 dna E E157 R161 E157 R161
BS03 ZN E H9 H13 C37 H9 H13 C37
BS04 ZZX E D64 S150 E157 D64 S150 E157
BS05 MG E D64 D121 D64 D121
BS06 MG E D64 E157 D64 E157
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7jn3, PDBe:7jn3, PDBj:7jn3
PDBsum7jn3
PubMed33712691
UniProtP03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

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