Structure of PDB 7f79 Chain E

Receptor sequence

>7f79E (length=448) Species: 237561 (Candida albicans SC5314)

LPHEPEFQQAYDELVSAVEDSTLFKEEPQYKKVIPVVSIPERIIQFRVTW
ENDKGEIEVNNGFRVQYNSALGPYKGGLRFHPTVNLSILKFLGFEQIFKN
ALTGLSMGGGKGGSDFNPKNRSDNEIRRFCVSFMRQLARYIGPDTDVPAG
DIGVGGREVGFLFGAYKQMRNNWAGVLTGKGLTWGGSLIRPEATGYGCVY
YVEKMIEKATNGKETFKGKRVAISGSGNVAQYAALKVIELGGTVVSLSDS
KGSIISKNGITADQVYAIAAAKLKFKSLEEIVADSVQLFSGDHSVEYLAG
VRPWTKVGQVDVALPSATQNEVSGEEAKALVDAGCKFIAEGSNMGSTKEA
IEVFEANRDSNGVWYAPGKAANCGGVAVSGLEMAQNSQRVQWTNEEVDAK
LKEIMYTCFENCYKTAQKYSILPSLLKGANIAGFIKVADAMFDQGDVF

3D structure

• PDB: 7f79 Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
• Chain: E
• Resolution: 2.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NDP	E	R81 K121 D153 I154 R192 T196 S228 G229 N230 V231 D251 S252 K274 A319 T320 G343 S344 N345 N374	R79 K119 D151 I152 R190 T194 S226 G227 N228 V229 D249 S250 K272 A317 T318 G341 S342 N343 N372
BS02	AKG	E	K77 G78 G79 Q98 K101 K113 A151 N345 V378 S381	K75 G76 G77 Q96 K99 K111 A149 N343 V376 S379

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0004353 glutamate dehydrogenase [NAD(P)+] activity
• GO:0004354 glutamate dehydrogenase (NADP+) activity
• GO:0016491 oxidoreductase activity
• GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

Biological Process

• GO:0006520 amino acid metabolic process
• GO:0006537 glutamate biosynthetic process
• GO:0008643 carbohydrate transport

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:7f79, PDBe:7f79, PDBj:7f79
• PDBsum: 7f79
• PubMed: 34271431
• UniProt: A0A1D8PMH8