Structure of PDB 7ea8 Chain E

Receptor sequence
>7ea8E (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQFKTDLRFQSAAI
GALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
3D structure
PDB7ea8 Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
ChainE
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R40 Y41 K64 R69 R2 Y3 K26 R31
BS02 dna E R42 R63 R72 R83 F84 T118 R4 R25 R34 R44 F45 T79
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ea8, PDBe:7ea8, PDBj:7ea8
PDBsum7ea8
PubMed33972509
UniProtQ6PI79|H33_XENLA Histone H3.3

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