Structure of PDB 7dgs Chain E

Receptor sequence
>7dgsE (length=176) Species: 9913 (Bos taurus) [Search protein sequence]
TYKYVNLREPSMDMKSVTDRAAQTLLWTELIRGLGMTLSYLFREPATINY
PFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRA
DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYN
KEKLLNNGDKWEAEIAANIQADYLYR
3D structure
PDB7dgs A Dynamic Substrate Pool Revealed by cryo-EM of a Lipid-Preserved Respiratory Supercomplex.
ChainE
Resolution7.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SF4 E C123 C152 I153 Y154 C155 G156 F157 C158 E169 C87 C116 I117 Y118 C119 G120 F121 C122 E133
BS02 SF4 E C113 I114 A115 C116 C119 C162 V164 I167 C77 I78 A79 C80 C83 C126 V128 I131
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:7dgs, PDBe:7dgs, PDBj:7dgs
PDBsum7dgs
PubMed34913730
UniProtP42028|NDUS8_BOVIN NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (Gene Name=NDUFS8)

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