Structure of PDB 7ch0 Chain E

Receptor sequence
>7ch0E (length=263) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
VANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLI
GGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNVFD
NVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAA
LARAIALEPDLIMFDQPFVGQDPITMGVLVKLISELNSALGVTCVVVSHD
VPEVLSIADHAWILADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPF
RYPAGDYHADLLP
3D structure
PDB7ch0 Structural mechanism of phospholipids translocation by MlaFEDB complex.
ChainE
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.6.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP E S143 E144 S146 G148 M149 S139 E140 S142 G144 M145
BS02 ATP E R18 S43 G44 G46 K47 T48 T49 R14 S39 G40 G42 K43 T44 T45
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0120014 phospholipid transfer activity
Biological Process
GO:0015914 phospholipid transport
GO:0120010 intermembrane phospholipid transfer
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:1990531 phospholipid-translocating ATPase complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7ch0, PDBe:7ch0, PDBj:7ch0
PDBsum7ch0
PubMed32884137
UniProtP63386|MLAF_ECOLI Intermembrane phospholipid transport system ATP-binding protein MlaF (Gene Name=mlaF)

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