Structure of PDB 7ccq Chain E

Receptor sequence
>7ccqE (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB7ccq Structural basis for nucleosome-mediated inhibition of cGAS activity.
ChainE
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E H39 R40 Y41 P43 V46 R49 K56 R63 K64 L65 R69 H2 R3 Y4 P6 V9 R12 K19 R26 K27 L28 R32
BS02 dna E H39 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 R116 V117 T118 M120 H2 Y4 R5 P6 T8 R26 R35 R46 F47 Q48 R79 V80 T81 M83
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ccq, PDBe:7ccq, PDBj:7ccq
PDBsum7ccq
PubMed33051594
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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