Structure of PDB 7byl Chain E

Receptor sequence
>7bylE (length=354) Species: 6100,9606 [Search protein sequence]
SAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQE
HQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKP
FCVIDFIVFVASVAVIAAGTATSALRSMRFLQILRMVRMDRRGGTWKLLG
SVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGT
ITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQE
QHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYDDIMPAVKTVI
RSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVD
QIVG
3D structure
PDB7byl Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs.
ChainE
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PT5 E P94 V103 R150 F174 R216 M217 R219 P21 V30 R77 F101 R138 M139 R141
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005216 monoatomic ion channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005267 potassium channel activity
GO:0005515 protein binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0007605 sensory perception of sound
GO:0008218 bioluminescence
GO:0042472 inner ear morphogenesis
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0009925 basal plasma membrane
GO:0016020 membrane
GO:0034702 monoatomic ion channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7byl, PDBe:7byl, PDBj:7byl
PDBsum7byl
PubMed33238160
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
P56696|KCNQ4_HUMAN Potassium voltage-gated channel subfamily KQT member 4 (Gene Name=KCNQ4)

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