Structure of PDB 6xpw Chain E

Receptor sequence
>6xpwE (length=157) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
HHGSMSNEQTFIAIKPDGVQRGLIGPIISRFENRGFKLVAMKLVSPPQSQ
LEQHYADLSDKPFFKGLVSYMLSGPICAMVWEGRDVVKTGRTILGATNPL
ASAPGTIRGDFAIDVGRNVCHGSDSVENAKKEIALWFKPEELISWKSATF
DWVYEKA
3D structure
PDB6xpw Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
ChainE
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K11 Y51 N114 H117 E128
Catalytic site (residue number reindexed from 1) K15 Y55 N118 H121 E132
Enzyme Commision number 2.7.4.6: nucleoside-diphosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 E K11 N114 H117 K15 N118 H121
Gene Ontology
Molecular Function
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0009117 nucleotide metabolic process
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0016310 phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6xpw, PDBe:6xpw, PDBj:6xpw
PDBsum6xpw
PubMed33089641
UniProtQ7Z8P9|NDK_ASPFU Nucleoside diphosphate kinase (Gene Name=ndk1)

[Back to BioLiP]