Structure of PDB 6xmx Chain E

Receptor sequence
>6xmxE (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
SCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGL
FYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVM
ATAMYLQMEHVVDTCRKFIKAS
3D structure
PDB6xmx Small-molecule-induced polymerization triggers degradation of BCL6.
ChainE
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 U52 E E81 C84 E75 C78
BS02 U52 E M51 A52 G55 Y58 Q113 E115 H116 M45 A46 G49 Y52 Q107 E109 H110
External links
PDB RCSB:6xmx, PDBe:6xmx, PDBj:6xmx
PDBsum6xmx
PubMed33208943
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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