Structure of PDB 6x9n Chain E

Receptor sequence
>6x9nE (length=305) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HRRIHFVGIGGAGMCGIAEVLLNLGYEVSGSDLKASAVTERLEKFGAQIF
IGHQAENADGADVLVVSSAINRANPEVASALERRIPVVPRAEMLAELMRY
RHGIAVAGTHGKTTTTSLIASVFAAGGLDPTFVIGGRLNAAGTNAQLGAS
RYLVAEADESDASFLHLQPMVAVVTNIDADHMATYGGDFNKLKKTFVEFL
HNLPFYGLAVMCVDDPVVREILPQIARPTVTYGLSEDADVRAINIRQEGM
RTWFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDEAIVQGL
SGFQG
3D structure
PDB6x9n Pseudomonas aeruginosa MurC with AZ5595
ChainE
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K126 R151 H195
Catalytic site (residue number reindexed from 1) K112 R137 H181
Enzyme Commision number 6.3.2.8: UDP-N-acetylmuramate--L-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UYD E H124 G125 T189 N190 Y246 H288 L291 N292 H110 G111 T175 N176 Y232 H274 L277 N278
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6x9n, PDBe:6x9n, PDBj:6x9n
PDBsum6x9n
PubMed
UniProtQ9HW02|MURC_PSEAE UDP-N-acetylmuramate--L-alanine ligase (Gene Name=murC)

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