Structure of PDB 6wz5 Chain E

Receptor sequence
>6wz5E (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6wz5 Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
ChainE
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E H39 R40 Y41 P43 G44 V46 A47 R49 K64 L65 P66 R69 H3 R4 Y5 P7 G8 V10 A11 R13 K28 L29 P30 R33
BS02 dna E R42 T45 R72 R83 F84 Q85 S86 R116 V117 T118 R6 T9 R36 R47 F48 Q49 S50 R80 V81 T82
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6wz5, PDBe:6wz5, PDBj:6wz5
PDBsum6wz5
PubMed32939087
UniProtP84233|H32_XENLA Histone H3.2

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