Structure of PDB 6v2f Chain E

Receptor sequence
>6v2fE (length=206) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PIVMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQDLNTML
NTVGGHQAAMQMLKETINEEAAEWDRLHPPGQMREPRGSDIAGTTSTLQE
QIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRD
YVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPGATLEE
MMTACQ
3D structure
PDB6v2f Clinical targeting of HIV capsid protein with a long-acting small molecule.
ChainE
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 QNG E N53 T54 L56 N57 Q63 M66 Q67 L69 K70 I73 N74 T107 Y130 N47 T48 L50 N51 Q57 M60 Q61 L63 K64 I67 N68 T94 Y117 MOAD: Kd=240pM
BS02 QNG E P38 S41 Y169 L172 R173 Q179 K182 N183 P32 S35 Y156 L159 R160 Q166 K169 N170 MOAD: Kd=240pM
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:6v2f, PDBe:6v2f, PDBj:6v2f
PDBsum6v2f
PubMed32612233
UniProtP12493|GAG_HV1N5 Gag polyprotein (Gene Name=gag)

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