Structure of PDB 6v19 Chain E

Receptor sequence

>6v19E (length=242) Species: 10090 (Mus musculus) [Search protein sequence]

AVFQTPNYHVTQVGNEVSFNCKQTLGHDTMYWYKQDSKKLLKIMFSYNNK
QLIVNETVPRRFSPQSSDKAHLNLRIKSVEPEDSAVYLCASSLDWASQNT
LYFGAGTRLSVLEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFP
DHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQ
NPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD

3D structure

PDB

6v19 The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	E	D30 N58 D109 W110	D28 N49 D94 W95

External links

PDB	RCSB:6v19, PDBe:6v19, PDBj:6v19
PDBsum	6v19
PubMed	33863750

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