Structure of PDB 6ult Chain E

Receptor sequence
>6ultE (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMP
3D structure
PDB6ult Cyclic peptides can engage a single binding pocket through highly divergent modes.
ChainE
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E W370 P371 V376 L381 H433 D434 M438 W25 P26 V31 L36 H88 D89 M93
External links
PDB RCSB:6ult, PDBe:6ult, PDBj:6ult
PDBsum6ult
PubMed33046654
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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