Structure of PDB 6sic Chain E

Receptor sequence

>6sicE (length=285) Species: 930945 (Sulfolobus islandicus REY15A) [Search protein sequence]

PYYAFAEPFFIHAITHLHVGSGSSVEEEIALPFQRDELGYPTIYASSLKG
AIKSFLLKEFPDKRDVIYKVLGEDENPEEASLGTFLDAILFAIPSRIIEI
DSAKPYVWVYVTTYELLKKVKLYLDSISQLSNASFSNLKNKIDTILAKEG
KNITLDSDLKSAILNEDFYVELEALNNKIPSIINAGVPLLVLEDSIGREV
INRSLIRVRRIRIDRDKKVVETGGLWSEEYVPMKTIFFSVLLGKESKESA
IFASCILRNLRYVILGGKETIGKGIVELRWVKDVI

3D structure

PDB

6sic Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.

Chain

Resolution

3.52 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	A31 T223 G224 L226 W227	A30 T222 G223 L225 W226
BS02	rna	E	V20 G21 G23 S47 S48 K50 G51 A52 K54 E74 D75 A81 S82 R211 I212 R213 I214 R216 K219 W227 L266 G267 G268 K269 E270 T271	V19 G20 G22 S46 S47 K49 G50 A51 K53 E73 D74 A80 S81 R210 I211 R212 I213 R215 K218 W226 L265 G266 G267 K268 E269 T270

Gene Ontology

	Biological Process
GO:0051607	defense response to virus

View graph for
Biological Process

External links

PDB	RCSB:6sic, PDBe:6sic, PDBj:6sic
PDBsum	6sic
PubMed	32730741
UniProt	F0NDX6

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