Structure of PDB 6se3 Chain E

Receptor sequence

>6se3E (length=528) Species: 32630 (synthetic construct)

KKVAIIGAGVSGLASIRSCLEEGLEPTCFERSDDIGGLWKFSDHAEEGRA
SIYQSVFTNSSKEMMCFPDFPYPDDFPNFMHNSKLQEYITAFAKEKNLLK
YIQFKTLVSSVNKRPDFSVTGQWDVTTEKDGKKESAVFDAVMICSGHHVY
PNLPKESFPGLKHFKGKCFHSRDYKEPGIFKGKRVLVIGLGNSGCDIATE
LSHTAEKVIISSRSGSWVMSRVWDDGYPWDMLFITRFETFLKNSLPTAIS
DWWYMKQMNARFKHENYGLMPLNGTLRKEPVFNDELPARILCGTVSIKPN
VKEFTETSAIFEDGTVFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTL
FKGIFPPLLEKPTLAVIGLVQSLGATIPTTDLQARWAAKVFANSCTLPTT
NEMMDDIDEKMGKKLKWFGQSQTLQTDYITYMDELGSFIGAKPNIPWLFL
TDPQLALEVFFGPCSPYQFRLMGPGKWDGARNAILTQWDRTLKPTRTRAV
GEAKRPSLFYNLLKILLFPVLLLAVLLA

3D structure

• PDB: 6se3 Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
• Chain: E
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	E	I8 G9 G11 S13 F31 E32 R33 G39 L40 W41 R51 T60 N61 S62 L109 V110 C146 S147 H150 A377 T378	I6 G7 G9 S11 F29 E30 R31 G37 L38 W39 R49 T58 N59 S60 L107 V108 C144 S145 H148 A375 T376
BS02	NAP	E	Y55 F59 N61 G191 L192 G193 N194 S195 D198 R215 E281 A328 T329 G330	Y53 F57 N59 G189 L190 G191 N192 S193 D196 R213 E279 A326 T327 G328

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Nov 26 21:19:33 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '6se3', asym_id = 'E', title = 'Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='6se3', asym_id='E', title='Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0004499,0050660,0050661', uniprot = '', pdbid = '6se3', asym_id = 'E'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004499,0050660,0050661', uniprot='', pdbid='6se3', asym_id='E')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>