Structure of PDB 6scu Chain E

Receptor sequence
>6scuE (length=316) Species: 1427 (Bacillus thermoproteolyticus) [Search protein sequence]
ITGTSTVGVGRGVLGDQKNINTTYSTYYYLQDNTRGNGIFTYDAKYRTTL
PGSLWADADNQFFASYDAPAVDAHYYAGVTYDYYKNVHNRLSYDGNNAAI
RSSVHYSQGYNNAFWNGSQMVYGDGDGQTFIPLSGGIDVVAHELTHAVTD
YTAGLIYQNESGAINEAISDIFGTLVEFYANKNPDWEIGEDVYTPGISGD
SLRSMSDPAKYGDPDHYSKRYTGTQDNGGVHINSGIINKAAYLISQGGTH
YGVSVVGIGRDKLGKIFYRALTQYLTPTSNFSQLRAAAVQSATDLYGSTS
QEVASVKQAFDAVGVK
3D structure
PDB6scu THERMOLYSIN IN COMPLEX WITH FRAGMENT J88
ChainE
Resolution1.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.27: thermolysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H142 H146 E166 H142 H146 E166
BS02 CA E D138 E177 D185 E187 E190 D138 E177 D185 E187 E190
BS03 CA E D57 D59 Q61 D57 D59 Q61
BS04 CA E E177 N183 D185 E190 E177 N183 D185 E190
BS05 CA E Y193 T194 I197 D200 Y193 T194 I197 D200
BS06 88B E A113 H142 E143 H146 Y157 E166 H231 A113 H142 E143 H146 Y157 E166 H231
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6scu, PDBe:6scu, PDBj:6scu
PDBsum6scu
PubMed
UniProtP00800|THER_BACTH Thermolysin (Gene Name=npr)

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