Structure of PDB 6rt8 Chain E

Receptor sequence
>6rt8E (length=305) Species: 4058 (Catharanthus roseus) [Search protein sequence]
DETIWDLSPYIKIFKDGRVERLHNSPYVPPSLNDPETGVSWKDVPISSQV
SARVYIPKEKLPIFVYVHGAGFCLESAFRSFFHTFVKHFVAETKVIGVSI
EYRLAPEHLLPAAYEDCWEALQWVASHVGLDTAIDKDPWIINYGDFDRLY
LAGDSPGANIVHNTLIRAGKEKLKGGVKILGAILYYPYFIIKLSDDFEYN
YTCYWKLAYPNAPGGMNNPMINPIAENAPDLAGYGCSRLLVTLVSMISTT
PDETKDINAVYIEALEKSGWKGELEVADFDADYFELFTLETEMGKNMFRR
LASFI
3D structure
PDB6rt8 Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids.
ChainE
Resolution2.19 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KJE E Y18 A82 G83 S172 P173 Y205 Y225 I268 Y304 Y10 A70 G71 S155 P156 Y188 Y204 I247 Y283
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016829 lyase activity
Biological Process
GO:0009820 alkaloid metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rt8, PDBe:6rt8, PDBj:6rt8
PDBsum6rt8
PubMed32066966
UniProtA0A2P1GIW2|CS_CATRO Catharanthine synthase (Gene Name=CS)

[Back to BioLiP]