Structure of PDB 6rft Chain E

Receptor sequence
>6rftE (length=406) Species: 36809 (Mycobacteroides abscessus) [Search protein sequence]
SELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFH
DGKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRH
QLADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTV
DLGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEE
LQKESGKVRFVLHYESDGTASGFAIYRPKPGWPNAELHVQEVLGTNPRSY
ARTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLV
DIPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDD
ADIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAP
SAPDDF
3D structure
PDB6rft Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO E V25 V85 R91 G93 L95 T96 E120 L122 I123 R126 V24 V84 R90 G92 L94 T95 E119 L121 I122 R125
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0034069 aminoglycoside N-acetyltransferase activity
Biological Process
GO:0030649 aminoglycoside antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6rft, PDBe:6rft, PDBj:6rft
PDBsum6rft
PubMed31254444
UniProtA0A1M9A4M7

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