Structure of PDB 6r8y Chain E

Receptor sequence
>6r8yE (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
VKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRF
QSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
A
3D structure
PDB6r8y DNA damage detection in nucleosomes involves DNA register shifting.
ChainE
Resolution4.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E V36 R41 Y42 G45 T46 V47 A48 R50 R64 L66 R84 V1 R6 Y7 G10 T11 V12 A13 R15 R29 L31 R49
BS02 dna E Y42 R43 R73 R84 Q86 R117 V118 T119 Y7 R8 R38 R49 Q51 R82 V83 T84
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6r8y, PDBe:6r8y, PDBj:6r8y
PDBsum6r8y
PubMed31142837
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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