Structure of PDB 6q84 Chain E

Receptor sequence
>6q84E (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRG
PIKFNVWDTAGLEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRD
LVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNF
EKPFLWLARKLIGDPNLEFVA
3D structure
PDB6q84 Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
ChainE
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP E G19 G20 T21 G22 K23 T24 T25 F35 E36 K37 K38 Y39 V40 A41 T42 N122 K123 D125 A151 K152 G12 G13 T14 G15 K16 T17 T18 F28 E29 K30 K31 Y32 V33 A34 T35 N115 K116 D118 A144 K145
BS02 MG E T24 T42 D65 T17 T35 D58
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006913 nucleocytoplasmic transport

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Molecular Function
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Biological Process
External links
PDB RCSB:6q84, PDBe:6q84, PDBj:6q84
PDBsum6q84
PubMed31023722
UniProtP62826|RAN_HUMAN GTP-binding nuclear protein Ran (Gene Name=RAN)

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