Structure of PDB 6pam Chain E

Receptor sequence

>6pamE (length=589) Species: 279238 (Novosphingobium aromaticivorans DSM 12444)

RHDGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKK
AVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDA
TRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNI
APTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREK
MNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSE
NSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLF
RPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVT
FDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYD
PWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGA
SRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTL
VKNPPILLFDEATSCLDTRTEQDILSTMRAVASHRTTISIAHRLSTIADS
DTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAAESA

3D structure

• PDB: 6pam A structural framework for unidirectional transport by a bacterial ABC exporter.
• Chain: E
• Resolution: 3.7 Å

Enzymatic activity

• Enzyme Commision number: 7.-.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	E	H132 R135 Y370 R374 G397 G399 K400 S401	H120 R123 Y358 R362 G385 G387 K388 S389

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042626 ATPase-coupled transmembrane transporter activity
• GO:0140359 ABC-type transporter activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0046689 response to mercury ion
• GO:0055085 transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:6pam, PDBe:6pam, PDBj:6pam
• PDBsum: 6pam
• PubMed: 32703810
• UniProt: Q2G506|ATM1_NOVAD ATM1-type heavy metal exporter (Gene Name=atm1)