Structure of PDB 6o7i Chain E

Receptor sequence

>6o7iE (length=279) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence]

PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGG
ARISSAFPYSGDTYYLPKPLSVEPALEGILRYTTAKRLRKAKYLDLKNFE
LALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVY
FLYSGPREVFDGYIAPAMRFLGDTGIGGKSTWGAGLFEVEFHEMKIDAPG
SEYSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPG
GMERLELGLSHEVYVYGLTFPLGVELPEG

3D structure

PDB

6o7i Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	R16 T23 G26 N30 S33 V41 P130 V132 V133 L134 R136 Q139 I143 Y144 G183 I184 G185 G186 G233 G234 W235 S236 K241 R243 H269 E270 Y272	R15 T22 G25 N29 S32 V40 P122 V124 V125 L126 R128 Q131 I135 Y136 G175 I176 G177 G178 G225 G226 W227 S228 K233 R235 H261 E262 Y264
BS02	rna	E	S141 I143	S133 I135

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0005515	protein binding

	Biological Process
GO:0051607	defense response to virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:6o7i, PDBe:6o7i, PDBj:6o7i
PDBsum	6o7i
PubMed	31326272
UniProt	B6YWC1\|CSM4_THEON CRISPR system Cms protein Csm4 (Gene Name=csm4)

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