Structure of PDB 6n7l Chain E

Receptor sequence

>6n7lE (length=340) Species: 1338011 (Elizabethkingia anophelis NUHP1)

IPKTMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVD
GDWPAKPKMPLIPGHEGVGIVVACGPDAMVKEGDAVGVPWLYSACGCCDY
CITGWETLCEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPIL
CAGVTVYKGLKETETKPGEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVA
DDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHGALITAVSPIAFKQG
IDVLRRKGTIALNGLPPGSFELPIFETVLKRITVRGSIVGTRKDLQEALD
FANEGLVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDIA

3D structure

• PDB: 6n7l Crystal structure of an alcohol dehydrogenase from Elizabethkingia anophelis NUHP1
• Chain: E
• Resolution: 2.1 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): C43 T45 H48 H66 C152
• Catalytic site (residue number reindexed from 1): C42 T44 H47 H65 C151
• Enzyme Commision number: 1.1.1.1: alcohol dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	E	C43 H44 T45 H48 C152 T156 G176 G178 G179 L180 D199 V200 T241 A242 V243 A247 N264 G265 L266 I289 V290	C42 H43 T44 H47 C151 T155 G175 G177 G178 L179 D198 V199 T240 A241 V242 A246 N263 G264 L265 I288 V289
BS02	ZN	E	C43 H66 C152	C42 H65 C151
BS03	ZN	E	C96 C99 C102 C110	C95 C98 C101 C109

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008270 zinc ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:6n7l, PDBe:6n7l, PDBj:6n7l
• PDBsum: 6n7l
• UniProt: A0A077EGR8