Structure of PDB 6mln Chain E

Receptor sequence
>6mlnE (length=235) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
QTVRIGTDTTYAPFSSKDAKGEFIGFDIDLGNEMCKRMQVKCTWVASDFD
ALIPSLKAKKIDAIISSLAITDKRQQEIAFSDKLYAADSRLIAAKGSPIQ
PTLESLKGKHVGVLQGSTQEAYANDNWRTKGVDVVAYANQDLIYSDLTAG
RLDAALQDEVAASEGFLKQPAGKEYAFAGPSVKDKKYFGDGTGVGLRKDD
TELKAAFDKALTELRQDGTYDKMAKKYFDFNVYGD
3D structure
PDB6mln The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.
ChainE
Resolution1.721 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ARG E D11 Y14 F52 S69 S70 A72 R77 L117 S120 T121 Q122 D161 D8 Y11 F49 S66 S67 A69 R74 L114 S117 T118 Q119 D158 MOAD: Kd=29nM
PDBbind-CN: -logKd/Ki=7.54,Kd=29nM
Gene Ontology
Biological Process
GO:0006865 amino acid transport
GO:0071705 nitrogen compound transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6mln, PDBe:6mln, PDBj:6mln
PDBsum6mln
PubMed31348608
UniProtP02911|ARGT_SALTY Lysine/arginine/ornithine-binding periplasmic protein (Gene Name=argT)

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