Structure of PDB 6m64 Chain E

Receptor sequence
>6m64E (length=193) Species: 9606 (Homo sapiens) [Search protein sequence]
VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGL
LSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQR
YGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIR
MSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGS
3D structure
PDB6m64 Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-beta signaling.
ChainE
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E G342 G343 N387 Q388 A391 A395 V398 W448 Q455 G77 G78 N122 Q123 A126 A130 V133 W183 Q190
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6m64, PDBe:6m64, PDBj:6m64
PDBsum6m64
PubMed33323411
UniProtQ15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (Gene Name=SMAD2)

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