Structure of PDB 6m4w Chain E

Receptor sequence
>6m4wE (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
DGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYA
YGATGHPGIIPPHATLVFDVELLKLE
3D structure
PDB6m4w Rational design and implementation of a chemically inducible heterotrimerization system.
ChainE
Resolution3.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RAP E F37 D38 F47 E55 V56 I57 W60 Y83 F5 D6 F15 E23 V24 I25 W28 Y51 BindingDB: IC50=0.600000nM,EC50=30nM,Ki=0.20nM
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:6m4w, PDBe:6m4w, PDBj:6m4w
PDBsum6m4w
PubMed32747768
UniProtP62942|FKB1A_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1A (Gene Name=FKBP1A)

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