Structure of PDB 6l9l Chain E

Receptor sequence
>6l9lE (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
GPHSMRYYETATSRRGLGEPRYTSVGYVDDKEFVRFDSDAENPRYEPQVP
WMEQEGPEYWERITQIAKGQEQWFRVNLRTLLGYYNQSAGGTHTLQRMYG
CDVGSDGRLLRGYEQFAYDGCDYIALNEDLRTWTAADMAAQITRRKWEQA
GAAEYYRAYLEGECVEWLHRYLKNG
3D structure
PDB6l9l Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
ChainE
Resolution2.399 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Y7 Y45 R62 I63 G69 Q70 W73 N77 L81 Y84 R97 Y99 T143 K146 W147 A152 Y155 Y156 Y159 W167 Y171 Y7 Y45 R62 I63 G69 Q70 W73 N77 L81 Y84 R97 Y99 T143 K146 W147 A152 Y155 Y156 Y159 W167 Y171
External links
PDB RCSB:6l9l, PDBe:6l9l, PDBj:6l9l
PDBsum6l9l
PubMed34074778
UniProtP01897|HA1L_MOUSE H-2 class I histocompatibility antigen, L-D alpha chain (Gene Name=H2-L)

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