Structure of PDB 6l4a Chain E

Receptor sequence
>6l4aE (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB6l4a Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
ChainE
Resolution12.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R40 Y41 R42 P43 G44 V46 R49 R63 L65 R69 D81 R83 R2 Y3 R4 P5 G6 V8 R11 R25 L27 R31 D43 R45
BS02 dna E R40 R42 R63 R72 R83 F84 Q85 R116 V117 T118 M120 R2 R4 R25 R34 R45 F46 Q47 R78 V79 T80 M82
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:6l4a, PDBe:6l4a, PDBj:6l4a
PDBsum6l4a
PubMed31711756
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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