Structure of PDB 6ivk Chain E

Receptor sequence
>6ivkE (length=271) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
IIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNS
ASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSW
SLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLRE
AAKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFC
TLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLN
AMCNTIERNLLDMTGQHPLPE
3D structure
PDB6ivk Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
ChainE
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H108 H111 H85 H88
BS02 ZN E D285 H290 D262 H267
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6ivk, PDBe:6ivk, PDBj:6ivk
PDBsum6ivk
PubMed31263784
UniProtW9BH30

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