Structure of PDB 6iro Chain E

Receptor sequence
>6iroE (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence]
RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAV
MALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6iro Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling.
ChainE
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R42 R63 R72 R83 F84 Q85 V117 T118 R3 R24 R33 R44 F45 Q46 V78 T79
BS02 dna E R40 Y41 R49 R63 L65 R69 R83 R1 Y2 R10 R24 L26 R30 R44
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6iro, PDBe:6iro, PDBj:6iro
PDBsum6iro
PubMed30872815
UniProtP84233|H32_XENLA Histone H3.2

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