Structure of PDB 6iqw Chain E

Receptor sequence
>6iqwE (length=277) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence]
PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAVEELVDAFVGG
ARISSAFPYSGDTYYLPKPLSVEPALEGILTGLDEEERYTTAKRLRKAKY
LDLKNFELALRLRPFTIPEEIPYARVDVPRVVLDRVTQDSSIYFWEEIRF
REKSGVYFLYSGPREVFDGYIAPAMRFLGWGAGLFEVEFHEMKIDAPGSE
YSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEGSIVKNDPGGM
ERLELGLSHEVYVYGLTFPLGVELPEG
3D structure
PDB6iqw Cryo-EM structure of Type III-A CRISPR effector complex.
ChainE
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E G26 G29 N30 V41 E42 P130 V132 V133 L134 R136 Q139 D140 I143 Y144 R231 K232 G233 G234 W235 S236 F237 R243 H269 V271 Y272 G25 G28 N29 V40 E41 P129 V131 V132 L133 R135 Q138 D139 I142 Y143 R221 K222 G223 G224 W225 S226 F227 R233 H259 V261 Y262
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6iqw, PDBe:6iqw, PDBj:6iqw
PDBsum6iqw
PubMed30459428
UniProtB6YWC1|CSM4_THEON CRISPR system Cms protein Csm4 (Gene Name=csm4)

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