Structure of PDB 6ipu Chain E

Receptor sequence
>6ipuE (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB6ipu PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
ChainE
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E H39 R40 Y41 P43 G44 V46 A47 R49 R63 K64 L65 P66 R69 R83 H2 R3 Y4 P6 G7 V9 A10 R12 R26 K27 L28 P29 R32 R46
BS02 dna E R40 Y41 R42 P43 T45 R72 R83 F84 Q85 R116 V117 T118 R3 Y4 R5 P6 T8 R35 R46 F47 Q48 R79 V80 T81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6ipu, PDBe:6ipu, PDBj:6ipu
PDBsum6ipu
PubMed31848352
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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