Structure of PDB 6ifz Chain E

Receptor sequence

>6ifzE (length=207) Species: 767463 (Streptococcus thermophilus ND03) [Search protein sequence]

TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSS
LKGKMRTLLAKVYNESDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELD
SLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENE
NQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVK
TLNELLT

3D structure

PDB

6ifz Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference

Chain

Resolution

3.58 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	G21 S50 K53 G54 K55 S86 E123 N124 T125 I126 A133 R136 Y181 G184 S185 S187 R188	G20 S49 K52 G53 K54 S76 E113 N114 T115 I116 A123 R126 Y171 G174 S175 S177 R178
BS02	rna	E	E132 A133 N134 P135 R136	E122 A123 N124 P125 R126

External links

PDB	RCSB:6ifz, PDBe:6ifz, PDBj:6ifz
PDBsum	6ifz
PubMed	30503210

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