Structure of PDB 6ifr Chain E

Receptor sequence

>6ifrE (length=205) Species: 767463 (Streptococcus thermophilus ND03) [Search protein sequence]

TFAKIKFSAQIRLETGLHIGGSDAFAAIGAINSPVIKDPITNLPIIPGSS
LKGKMRTLLAKVYNDILSRLFGNSKDKRFKMGRLIFRDAFLSNADELDSL
GVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFELIYEITDENENQ
VEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFENLKATTVFGNYDVKTL
NELLT

3D structure

PDB

6ifr Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	I20 G21 D24 S50 S51 K53 G54 R57 G84 S86 M93 F122 E123 N124 T125 I126 A133 R136 Y181 G183 G184 S185 R188	I19 G20 D23 S49 S50 K52 G53 R56 G72 S74 M81 F110 E111 N112 T113 I114 A121 R124 Y169 G171 G172 S173 R176
BS02	rna	E	I29 N33 E132 A133 N134 P135 R136	I28 N32 E120 A121 N122 P123 R124

External links

PDB	RCSB:6ifr, PDBe:6ifr, PDBj:6ifr
PDBsum	6ifr
PubMed	30503210

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