Structure of PDB 6hks Chain E

Receptor sequence
>6hksE (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
DSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLN
EGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRR
3D structure
PDB6hks Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
ChainE
Resolution2.19441 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E K520 F521 G522 F523 N524 L525 K526 Q531 S538 H572 D573 K16 F17 G18 F19 N20 L21 K22 Q27 S34 H68 D69
External links
PDB RCSB:6hks, PDBe:6hks, PDBj:6hks
PDBsum6hks
PubMed31092861
UniProtP26045|PTN3_HUMAN Tyrosine-protein phosphatase non-receptor type 3 (Gene Name=PTPN3)

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