Structure of PDB 6ghv Chain E

Receptor sequence
>6ghvE (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
LCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQN
FLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNV
GEEDCAEFSGNGWNDDKCNLAKFWICKKSAASC
3D structure
PDB6ghv Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis.
ChainE
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EZ8 E Q264 G265 Q13 G14 MOAD: Kd=52uM
BS02 EZ8 E F313 E347 N349 V351 G352 E354 E358 N365 D367 F62 E96 N98 V100 G101 E103 E107 N114 D116 MOAD: Kd=52uM
BS03 CA E E347 N349 E354 N365 D366 E96 N98 E103 N114 D115
BS04 CA E D320 E324 N350 E354 D355 D69 E73 N99 E103 D104
BS05 EZ8 E N272 R309 S310 N311 R312 F374 N21 R58 S59 N60 R61 F123 MOAD: Kd=52uM
External links
PDB RCSB:6ghv, PDBe:6ghv, PDBj:6ghv
PDBsum6ghv
PubMed31469191
UniProtQ9NNX6|CD209_HUMAN CD209 antigen (Gene Name=CD209)

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