Structure of PDB 6gh1 Chain E

Receptor sequence
>6gh1E (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRW
3D structure
PDB6gh1 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
ChainE
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E D69 H155 D69 H155
BS02 peptide E Y7 H9 Y59 R62 E63 I73 N77 Y84 W97 S143 E152 Q156 Y159 W167 Y171 Y7 H9 Y59 R62 E63 I73 N77 Y84 W97 S143 E152 Q156 Y159 W167 Y171
External links
PDB RCSB:6gh1, PDBe:6gh1, PDBj:6gh1
PDBsum6gh1
PubMed30087334
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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