Structure of PDB 6e3l Chain E

Receptor sequence
>6e3lE (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
SQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTA
DIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWV
TMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYV
HYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVG
HLSNISCYETMAD
3D structure
PDB6e3l Structure of the IFN gamma receptor complex guides design of biased agonists.
ChainE
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CYS E C174 P191 C147 P164
External links
PDB RCSB:6e3l, PDBe:6e3l, PDBj:6e3l
PDBsum6e3l
PubMed30814731
UniProtP38484|INGR2_HUMAN Interferon gamma receptor 2 (Gene Name=IFNGR2)

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