Structure of PDB 6dn8 Chain E

Receptor sequence
>6dn8E (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]
RPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQ
STDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTAL
VGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFEAFALPDSLLVVLDMDEG
TLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDP
3D structure
PDB6dn8 A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ChainE
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E R77 P79 V80 A81 G110 T111 Y129 V216 W217 G218 R45 P47 V48 A49 G78 T79 Y97 V180 W181 G182
External links
PDB RCSB:6dn8, PDBe:6dn8, PDBj:6dn8
PDBsum6dn8
PubMed30226743
UniProtQ96A44|SPSB4_HUMAN SPRY domain-containing SOCS box protein 4 (Gene Name=SPSB4)

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