Structure of PDB 6c1v Chain E

Receptor sequence
>6c1vE (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYL
GNTVDLSSFDFRTGKMMP
3D structure
PDB6c1v Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R166 K167 S168 G169 D176 K186 R188 R19 K20 S21 G22 D29 K39 R41 PDBbind-CN: Kd=13uM
BS02 dna E S189 K190 P191 S42 K43 P44 PDBbind-CN: Kd=13uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1v, PDBe:6c1v, PDBj:6c1v
PDBsum6c1v
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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