Structure of PDB 6bbn Chain E

Receptor sequence
>6bbnE (length=378) Species: 9606 (Homo sapiens) [Search protein sequence]
SNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRG
SLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPK
QKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCF
AYGQTGSGKTHTMGGDSKGIYALAARDVFLMLKKPNYKKLELQVYATFFE
IYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGN
SCRTSAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQT
RLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRT
CMIATISPGMASCENTLNTLRYANRVKE
3D structure
PDB6bbn Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.
ChainE
Resolution3.514 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP E R229 T315 G316 G318 K319 T320 H321 S432 S433 G460 R69 T155 G156 G158 K159 T160 H161 S258 S259 G286
BS02 MG E T320 S433 D457 T160 S259 D283
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:6bbn, PDBe:6bbn, PDBj:6bbn
PDBsum6bbn
PubMed29980677
UniProtO00139|KIF2A_HUMAN Kinesin-like protein KIF2A (Gene Name=KIF2A)

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