Structure of PDB 6ati Chain E

Receptor sequence
>6atiE (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEYSTSECHFFNGTERVRFLERYFHNQEENVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTV
YPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAT
3D structure
PDB6ati Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
ChainE
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E E9 F26 Y30 N37 D57 Y60 W61 Q70 R71 Y78 H81 N82 V85 E8 F25 Y29 N36 D56 Y59 W60 Q69 R70 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ati, PDBe:6ati, PDBj:6ati
PDBsum6ati
PubMed28801345
UniProtA0A0A1I7H6

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