Structure of PDB 6atf Chain E

Receptor sequence
>6atfE (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEYSTSECHFFNGTERVRFLERYFHNQEENVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVHPKVTV
YPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB6atf Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
ChainE
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E E9 S11 T12 S13 E28 Y30 N37 D57 Y60 W61 R71 Y78 H81 N82 V85 E8 S10 T11 S12 E27 Y29 N36 D56 Y59 W60 R70 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6atf, PDBe:6atf, PDBj:6atf
PDBsum6atf
PubMed28801345
UniProtA0A0A1I7H6

[Back to BioLiP]